Electrospinning was used to synthsize nanofibers to be used as gas sensing materials. An electrospinning device with double nozzles of opposite polarities was designed for the synthesis of SnO2/In2O3 hetero-nanofibers in our experiments. It also included two syringes with different solutions connected to the bipolarity nozzles, and a collection plate connected to the ground. In this work, the Matrix Laboratory (MATLAB) software was used to simulate the motion locus of the bipolarity double-nozzle electrospinning process. The charged solutions were simulated as multiply charged and discretized particles. Then, force analysis was carried out for the charged particles composing the electrospun fibers, and a molecular dynamics model was built. The motion locus of the opposite electrically charged particles was calculated and simulated on the basis of the Runge–Kutta algorithm. Nanofibers with opposite polarities were attracted to and intertwined with each other and then descended to the collection plate because of gravity. The motion locus of the organic composite nanofibers synthesized using the bipolarity double-nozzle electrospinning device is shown to be identical to the simulated motion locus.