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Notice of retraction
Vol. 34, No. 8(3), S&M3042

Notice of retraction
Vol. 32, No. 8(2), S&M2292

Print: ISSN 0914-4935
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
Sensors and Materials
is covered by Science Citation Index Expanded (Clarivate Analytics), Scopus (Elsevier), and other databases.

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Sensors and Materials, Volume 30, Number 11(3) (2018)
Copyright(C) MYU K.K.
pp. 2693-2701
S&M1710 Research Paper of Special Issue
https://doi.org/10.18494/SAM.2018.2007
Published: November 30, 2018

Silicon Nanowire Microfluidic Biosensor for Multiplexed Biomolecule Detection [PDF]

Anran Gao, Yuelin Wang, and Tie Li

(Received May 25, 2018; Accepted September 10, 2018)

Keywords: silicon nanowire, microfluidic system, multiplexed detection, biosensor

The integration of a microfluidic sample delivery chip with a silicon nanowire (SiNW) biosensor device for multiplexed biomolecule detection was demonstrated. The SiNWs and polydimethylsiloxane (PDMS) chips were fabricated by complementary metal oxide semiconductor (CMOS) compatibility methods at a low cost. They were integrated together by using optimal O2 plasma parameters that enabled rapid and leakage-free bond formation, without additional heating or applied pressure. The capillary action induced by the hydrophilicity of the channels using polyvinylpyrrolidone (PVP) was demonstrated to allow analyte solution delivery onto the sensor array directly, without the need of using external pumping devices. The multiplexed, real-time, and label-free electrical biomolecule detection was demonstrated with high sensitivity and selectivity. The novel detection approach enables simple and rapid multiplexed biomarker detection, showing great promise for application in point-of-care disease diagnostics.

Corresponding author: Tie Li


Cite this article
Anran Gao, Yuelin Wang, and Tie Li, Silicon Nanowire Microfluidic Biosensor for Multiplexed Biomolecule Detection, Sens. Mater., Vol. 30, No. 11, 2018, p. 2693-2701.



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