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Notice of retraction
Vol. 34, No. 8(3), S&M3042

Notice of retraction
Vol. 32, No. 8(2), S&M2292

Print: ISSN 0914-4935
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
Sensors and Materials
is covered by Science Citation Index Expanded (Clarivate Analytics), Scopus (Elsevier), and other databases.

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Sensors and Materials, Volume 25, Number 9 (2013)
Copyright(C) MYU K.K.
pp. 667-671
S&M960 Research Paper of Special Issue
https://doi.org/10.18494/SAM.2013.918
Published: December 16, 2013

Optimization of Microfluidic Immunomagnetic Chip for Circulating Tumor Cell Capture [PDF]

Xiang Chen, Jinquan Liu, Jun Zhu, Yunfan Sun and Jia Fan

(Received June 10, 2013; Accepted September 9, 2013)

Keywords: immunomagnetic, CTC, microfluidic

The enumeration of circulating tumor cells (CTCs) has proved valuable for early detection and prognosis in cancer treatment. In this work, an optimized design of a microfluid-based immunomagnetic chip is proposed to separate CTCs from whole blood. Unlike most reported immunomagnetic-based methods in which the magnetic field is applied perpendicular to the flow direction, here, the magnetic field is applied parallel to the flow direction, which makes the hydrodynamic force not the dominant force to hamper cell capture. Experimental validation showed that this novel chip can be operated at a flow rate of up to 6 ml/h with 90% CTC capture efficiency.

Corresponding author: Xiang Chen


Cite this article
Xiang Chen, Jinquan Liu, Jun Zhu, Yunfan Sun and Jia Fan, Optimization of Microfluidic Immunomagnetic Chip for Circulating Tumor Cell Capture, Sens. Mater., Vol. 25, No. 9, 2013, p. 667-671.



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